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Effective control of breast cancer depends on three types of
research accomplishment -- understanding the disease's origins and
progression: successfully applying this knowledge to methods of
detection, diagnosis and treatment: and finding ways to make these
advances truly available to the public as effectively as possible.
The significant progress that is occurring across this entire
spectrum of pioneering investigation is reflected in these
proceedings of the 1987 biennial conference of the International
Association for Breast Cancer Research. The first section of the
book focuses on oncogenes and chemical effectors that may play key
roles in early cell transformation leading to breast cancer.
Research discussed includes identification of specific oncogenes
which appear to be involved in the disease, study of their
activation and expression, examination of the biological effects of
various growth factors isolated from breast cancer cell lines, and
investigation of the molecular mechanisms by which estrogens
promote and stimulate growth of breast cancers. The second group of
chapters deals with several other complex factors and phenomena
which may influence tumor formation in the breast, for example,
expression of abnormalities by fibroblasts, disruption of
epithelial-mesenchymal interactions, and loss of ability nili to
synthesize normal basal lamina resulting in alterations in the
extracellular matrix. Clarification of the processes of normal
mammary gland development and differentiation is central to much of
this work.
Since Freud first began his journey into Psychoanalysis the Talking
Therapies have grown exponentially. Training is rigorous and
conforms to exacting rules and regulations such as those
commensurate within the British Association of Counselling and
Psychotherapy (2010), which are intended to protect the client and
counsellor alike Therefore, this work questions why the role of
humour in therapy is poorly understood, to verify if humour is
used, whether it is taught and if there is evidence of its benefits
and general awareness? Anecdotal evidence is reviewed and the
benefits/negatives of humour are also cited, however, due to the
paucity of research its dearth is prominent. Findings support that
humour was only mentioned in training but still used by virtually
all within therapy session. Lack of research, training, and
awareness therefore indicates that humour as a medium in therapy is
indeed poorly understood. This work may shed some light to those;
considering talking therapy whether qualified or not, those
deciding on research to enlighten this under-researched subject and
those genuinely interested in this exciting concept.
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RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding - Proceedings of the International Conference on RNA Tumor Viruses in Human Cancer, Denver, Colorado, June 10-14, 1984 (Paperback, Softcover reprint of the original 1st ed. 1985)
Philip Furmanski, Jean Carol Hager, Marvin A. Rich
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R5,801
Discovery Miles 58 010
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Ships in 10 - 15 working days
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We stand today on the threshold of a new understanding of cancer.
Primarily through the powerful tools of molecular biology, unified
hypotheses explaining the origins of the disease are emerging and
rapidly being validated. This volume, which presents the latest
findings from laboratories throughout the world on the role of RNA
tumor viruses in cancer, is a celebration of these achievements and
a prediction of further progress leading ultimately to the control
of the disease. It is important in this context to recall the
natural history or life cycle of RNA cancer virology. From the
earliest days of the science, when viruses were first recognized as
distinct biologic agents of etiologic significance, their role in
cancer was proposed and hotly debated. The critical early
discoveries, even those made as recently as 25 years ago, were met
with rejection; not skepticism or cautious restraint, but outright
rejection. During the 60's, there was a gradual acceptance of the
association between viruses and cancer, the result of landmark
studies in experimental systems, and this led to a frenzy of
activity in the field. There followed another period of doubt and
uncertainty, due to the difficulty in attempting to apply directly,
and in retrospect inappropriately, the tenets of infectious disease
to human cancers, only to have the field resurrected, revitalized
and redirected by the explosion of progress in molecular biology
and genetics.
In breast cancer as in other cancers on the front line of modern
interdisciplinary research we have crossed the threshhold of new
understanding. Fueled by an awareness that breast cancer is a
leading cause of morbidity and mortality in women and honed by
rapid technological advances in molecular mechanisms, major inroads
into the darkness of this scourge have been accomplished during the
past several years. Basic laboratory and clinical research findings
must influence and in turn be influenced by efforts to detect, to
diagnose and to cure the human disease. It is indeed gratifying to
note that the efforts of scientists and clinicians from throughout
the world reported in this volume are achieving this objective. The
first section of the book focuses on the molecular and genetic
basis of breast cancer. The role of specific oncogenes in mammary
tumorigenesis using transgenic mice and mammary glands correlating
molecular events with specific stages in neoplastic development are
described and discussed. Such topics as the nature of specific
oncogenes, levels of oncogene expression, the alteration of
expression of other growth regulatory genes and the state of the
cell in which the oncogene is expressed are specifically addressed.
This section of the book is rounded out with discussions on the
potential of genetic alterations as indicators of prognosis, the
characterization of full-length cDNA codes for breast cancer
markers and the function of antigens in tuomorigenesis.
The control of breast cancer, a leading cause of cancer death in
women, will depend ultimately on our understanding of the
disease--its origin, and progression which in turn will permit the
effective management of its treatment, its detection, and perhaps
even its prevention. It is for a better understanding of this
spectrum of biological processes crossing back and forth across
scientific and clinical disciplines that this volume strives.
Several broad topics have been addressed in organizing a large mass
of work representing state of the art updates from many of the
major breast cancer research groups around the world. The chapters
in the first section speak to the factors affecting the growth and
development of normal and malignant mammary epithelium. Special
emphasis is placed on insights drawn from developmental biology,
the cellular interactions that occur in the mammary gland during
growth and differentiation; and the study of hormones and growth
factors in the regulation of growth and differentiation of normal
and malignant breast tissues. In the section on the biology of
breast cancer, there is a characterization of relevant model
systems for the study of breast cancer and their contribution to
our understanding of preneoplasia and progression in mammary
cancer. Included as well is the current status of major studies on
the immunological aspects of breast cancer and the latest efforts
in the development of markers for metastasis in breast cancer.
In breast cancer as in other cancers on the front line of modern
interdisciplinary research we have crossed the threshhold of new
understanding. Fueled by an awareness that breast cancer is a
leading cause of morbidity and mortality in women and honed by
rapid technological advances in molecular mechanisms, major inroads
into the darkness of this scourge have been accomplished during the
past several years. Basic laboratory and clinical research findings
must influence and in turn be influenced by efforts to detect, to
diagnose and to cure the human disease. It is indeed gratifying to
note that the efforts of scientists and clinicians from throughout
the world reported in this volume are achieving this objective. The
first section of the book focuses on the molecular and genetic
basis of breast cancer. The role of specific oncogenes in mammary
tumorigenesis using transgenic mice and mammary glands correlating
molecular events with specific stages in neoplastic development are
described and discussed. Such topics as the nature of specific
oncogenes, levels of oncogene expression, the alteration of
expression of other growth regulatory genes and the state of the
cell in which the oncogene is expressed are specifically addressed.
This section of the book is rounded out with discussions on the
potential of genetic alterations as indicators of prognosis, the
characterization of full-length cDNA codes for breast cancer
markers and the function of antigens in tuomorigenesis.
Effective control of breast cancer depends on three types of
research accomplishment -- understanding the disease's origins and
progression: successfully applying this knowledge to methods of
detection, diagnosis and treatment: and finding ways to make these
advances truly available to the public as effectively as possible.
The significant progress that is occurring across this entire
spectrum of pioneering investigation is reflected in these
proceedings of the 1987 biennial conference of the International
Association for Breast Cancer Research. The first section of the
book focuses on oncogenes and chemical effectors that may play key
roles in early cell transformation leading to breast cancer.
Research discussed includes identification of specific oncogenes
which appear to be involved in the disease, study of their
activation and expression, examination of the biological effects of
various growth factors isolated from breast cancer cell lines, and
investigation of the molecular mechanisms by which estrogens
promote and stimulate growth of breast cancers. The second group of
chapters deals with several other complex factors and phenomena
which may influence tumor formation in the breast, for example,
expression of abnormalities by fibroblasts, disruption of
epithelial-mesenchymal interactions, and loss of ability nili to
synthesize normal basal lamina resulting in alterations in the
extracellular matrix. Clarification of the processes of normal
mammary gland development and differentiation is central to much of
this work.
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RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding - Proceedings of the International Conference on RNA Tumor Viruses in Human Cancer, Denver, Colorado, June 10-14, 1984 (Hardcover, 1985 ed.)
Philip Furmanski, Jean Carol Hager, Marvin A. Rich
|
R5,832
Discovery Miles 58 320
|
Ships in 10 - 15 working days
|
We stand today on the threshold of a new understanding of cancer.
Primarily through the powerful tools of molecular biology, unified
hypotheses explaining the origins of the disease are emerging and
rapidly being validated. This volume, which presents the latest
findings from laboratories throughout the world on the role of RNA
tumor viruses in cancer, is a celebration of these achievements and
a prediction of further progress leading ultimately to the control
of the disease. It is important in this context to recall the
natural history or life cycle of RNA cancer virology. From the
earliest days of the science, when viruses were first recognized as
distinct biologic agents of etiologic significance, their role in
cancer was proposed and hotly debated. The critical early
discoveries, even those made as recently as 25 years ago, were met
with rejection; not skepticism or cautious restraint, but outright
rejection. During the 60's, there was a gradual acceptance of the
association between viruses and cancer, the result of landmark
studies in experimental systems, and this led to a frenzy of
activity in the field. There followed another period of doubt and
uncertainty, due to the difficulty in attempting to apply directly,
and in retrospect inappropriately, the tenets of infectious disease
to human cancers, only to have the field resurrected, revitalized
and redirected by the explosion of progress in molecular biology
and genetics.
This is a reproduction of a book published before 1923. This book
may have occasional imperfections such as missing or blurred pages,
poor pictures, errant marks, etc. that were either part of the
original artifact, or were introduced by the scanning process. We
believe this work is culturally important, and despite the
imperfections, have elected to bring it back into print as part of
our continuing commitment to the preservation of printed works
worldwide. We appreciate your understanding of the imperfections in
the preservation process, and hope you enjoy this valuable book.
++++ The below data was compiled from various identification fields
in the bibliographic record of this title. This data is provided as
an additional tool in helping to ensure edition identification:
++++ L'honneur Est Sauf 2 Jean Carol
This is an EXACT reproduction of a book published before 1923. This
IS NOT an OCR'd book with strange characters, introduced
typographical errors, and jumbled words. This book may have
occasional imperfections such as missing or blurred pages, poor
pictures, errant marks, etc. that were either part of the original
artifact, or were introduced by the scanning process. We believe
this work is culturally important, and despite the imperfections,
have elected to bring it back into print as part of our continuing
commitment to the preservation of printed works worldwide. We
appreciate your understanding of the imperfections in the
preservation process, and hope you enjoy this valuable book.
This is a reproduction of a book published before 1923. This book
may have occasional imperfections such as missing or blurred pages,
poor pictures, errant marks, etc. that were either part of the
original artifact, or were introduced by the scanning process. We
believe this work is culturally important, and despite the
imperfections, have elected to bring it back into print as part of
our continuing commitment to the preservation of printed works
worldwide. We appreciate your understanding of the imperfections in
the preservation process, and hope you enjoy this valuable book.
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